Adverse Reactions of Artificial Bone Graft Substitutes: Lessons Learned From Using Tricalcium Phosphate geneX®

Letter to the Editor: Adverse Reactions of Artificial Bone Graft Substitutes: Lessons Learned From Using Tricalcium Phosphate geneX®

To the editor: The paper by Friesenbichler and colleagues [2] reported the findings of a truncated clinical study involving 31 patients treated for bone tumors by curettage, and filling of the defect using geneX (Biocomposites Ltd., Staffordshire, UK). ‘‘The reconstructive approach after intralesional curettage is controversial and clinical practice varies,’’ the authors reported. ‘‘Polymethylm...

Comparison of Apatite-Wollastonite Glass-Ceramic and β-tricalcium Phosphate used as Bone Graft Substitutes after Curettage of Bone Cysts

Comparison of hydroxyapatite and beta tricalcium phosphate as bone substitutes after excision of bone tumors.

Long-term results are reported in 23 patients and short-term results in 30 patients presenting with bone tumors treated by curettage or resection followed by implantation of hydroxyapatite (HA) or highly purified beta-tricalcium phosphate (beta-TCP), respectively. Mean follow-up was 97 and 26 months in cases involving HA implantation and beta-TCP implantation, respectively. Radiographs revealed...

Bone-grafting and bone-graft substitutes.

Bone grafts are often necessary to provide support, fill voids, and enhance biologic repair of skeletal defects. Autogenous bone recovered from the patient’s own iliac crest is generally considered the gold standard of bone grafts. There is a need for alternatives, however, because of limited autograft quantities, donor site morbidity, and other problems including limited biologic performance. ...

3D Printing of Octacalcium Phosphate Bone Substitutes

Biocompatible calcium phosphate ceramic grafts are able of supporting new bone formation in appropriate environment. The major limitation of these materials usage for medical implants is the absence of accessible methods for their patient-specific fabrication. 3D printing methodology is an excellent approach to overcome the limitation supporting effective and fast fabrication of individual comp...